The HIST2H2AA4 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The HIST2H2AA4 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling